Actively Recruiting

Age: 40Years - 75Years
All Genders
Healthy Volunteers
NCT05253560

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Led by Shaare Zedek Medical Center · Updated on 2026-04-29

600

Participants Needed

1

Research Sites

711 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Objective of the trial. To define a sub-population which is at increased risk of developing Parkinson, beyond the fact of carrying Gaucher; in this sub-population the investigators shall conduct a comprehensive evaluation that includes a variety of non-invasive tests, whose purpose is to evaluate the state of the pre- Parkinson's disease signs, signs which can appear, even twenty years before the appearance of the disease, and also to compare them to a group of diagnosed Gaucher patients and a group of healthy people who are not carriers of Gaucher disease. A group of those carriers will be available for trial or for treatment, if there will be a medicine for the prevention of the development of Parkinson, obtainable.

CONDITIONS

Official Title

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Who Can Participate

Age: 40Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to participate
Not Eligible

You will not qualify if you...

  • Diagnosis of Parkinson's disease
  • Diagnosis of dementia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Michal Becker- Cohen

Jerusalem, Please Select..., Israel, 9103102

Actively Recruiting

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Research Team

A

Ari Zimran, MD

CONTACT

M

Michal Becker- Cohen, M.Sc.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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