Actively Recruiting
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Led by Johns Hopkins University · Updated on 2025-09-23
70
Participants Needed
1
Research Sites
435 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators propose a pilot crossover trial of 2 behavioral language treatments, with randomized order of treatments and blinded assessors, to determine if a therapy designed to stimulate right hemisphere functions (Producing Increasingly Complex Themes Using Right-hemisphere Engagement Implemented with Telemedicine - PICTURE IT; described below) is more effective in improving discourse than a published computer delivered lexical treatment (shown previously to improve naming) in subacute post-stroke aphasia.
CONDITIONS
Official Title
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Premorbid proficiency in English
- Left hemisphere ischemic or hemorrhagic stroke confirmed by imaging, occurring either 1-4 months or 63 6 months ago
- Diagnosis of aphasia secondary to stroke defined by Western Aphasia Battery-Revised Aphasia Quotient < 93.8
- Capable of giving informed consent or indicating another to provide consent
You will not qualify if you...
- Prior neurologic disease affecting the brain other than stroke (e.g., brain tumor, multiple sclerosis, traumatic brain injury)
- Prior severe psychiatric illness, developmental disorders, or intellectual disability (e.g., PTSD, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders)
- Inability to follow treatment procedures as indicated by appropriate engagement during probes
- Uncorrected severe visual or hearing loss by self-report and medical records
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins School of Medicine
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
A
Argye E Hillis, MD
CONTACT
M
Melissa D Stockbridge, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here