Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07214389

PRoducing Outcome Measures for OTP Quality Improvement

Led by RTI International · Updated on 2026-04-21

4500

Participants Needed

1

Research Sites

112 weeks

Total Duration

On this page

Sponsors

R

RTI International

Lead Sponsor

U

University of California, Los Angeles

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet many people leave treatment early. The project will compare two approaches that provide clinics with retention/outcome quality measures and a quality-improvement (QI) toolkit-either alone or with added facilitation-against usual care. Forty-five BayMark OTPs in multiple states will be randomly assigned to one of three groups: (1) quality measures + QI toolkit; (2) quality measures + QI toolkit + external QI facilitation; or (3) usual care. The primary outcome is 90-day retention in treatment, measured from OTP electronic health records and Medicaid claims. Secondary outcomes include emergency department visits, hospitalizations, overdoses, and mortality. Findings will identify practical, scalable strategies to improve patient retention in OTPs.

CONDITIONS

Official Title

PRoducing Outcome Measures for OTP Quality Improvement

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be treated at BayMark opioid treatment programs (OTPs).
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

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Trial Site Locations

Total: 1 location

1

RTI International

Research Triangle Park, North Carolina, United States, 27709

Actively Recruiting

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Research Team

T

Tami L Mark, PhD

CONTACT

E

Emily C Costilow, MA, PMP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

3

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