Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05380414

Profiling Program of Advanced/Metastatic Pancreatic Cancer Patients

Led by Centre Leon Berard · Updated on 2026-03-31

750

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The proposal is to implement a molecular screening program for advanced/metastatic pancreatic cancer patients before the initiation of 1st line treatment in order to allow a better selection of patients for rationale personalized medicine with targeted agents and/or combination involving a chemotherapy backbone.

CONDITIONS

Official Title

Profiling Program of Advanced/Metastatic Pancreatic Cancer Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female patient > 18 years
  • Metastatic or advanced pancreatic ductal adenocarcinoma (PDAC)
  • Patient pretreated with no more than one prior systemic chemotherapy for metastatic/advanced disease
  • Availability of an archival representative FFPE tumor sample from primary tumor or metastatic lesion with associated pathology report
  • Life expectancy greater than 3 months
  • Performance status (PS) score of 0 or 1
Not Eligible

You will not qualify if you...

  • Curative therapy available
  • Any condition contraindicating blood sampling procedures required by the protocol
  • Known additional malignancy that is progressing or requires active treatment, except adequately treated basal cell carcinoma, squamous cell carcinoma of the skin, or in situ cervical cancer
  • Psychological, familial, geographic, or social situations potentially preventing informed consent or compliance with study procedures according to investigator judgment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Léon Bérard

Lyon, France, 69373

Actively Recruiting

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Research Team

P

Philippe CASSIER, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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Profiling Program of Advanced/Metastatic Pancreatic Cancer Patients | DecenTrialz