Actively Recruiting
Progesterone-modified Natural Cycle for FET
Led by Shandong University of Traditional Chinese Medicine · Updated on 2026-04-29
336
Participants Needed
1
Research Sites
195 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hormone replacement therapy (HRT) cycles, despite the ease of synchronizing embryo thawing and embryo transfer timing, increase the risk of pregnancies and obstetric complications compared to natural cycles (NC). By ensuring the presence of the corpus luteum while reducing the number of monitoring sessions, the progesterone modified natural cycle (P4mNC) offers more convenience for the patient than the normal NC. This study is designed to compare the effects of P4mNC and HRT cycles on FET outcomes.
CONDITIONS
Official Title
Progesterone-modified Natural Cycle for FET
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 21 to 44 years undergoing frozen blastocyst transfer
- Body mass index (BMI) between 18 and 35 kg/m2
- Having regular ovulatory cycles
You will not qualify if you...
- Untreated uterine adhesions
- Medical contraindications to estrogen and progesterone therapy
- Illnesses contraindicating assisted reproductive technology or pregnancy
- History of recurrent implantation failures (more than 2 embryo transfer failures)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Jinan, Shandong, China, 250014
Actively Recruiting
Research Team
X
Xian-Ling Cao, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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