Observing Visual Outcomes After Different Types of Posterior Lamellar Keratoplasty for Corneal Diseases

What this Trial Is About

Researchers are studying Fuchs Endothelial Corneal Dystrophy and Pseudophakic Bullous Keratopathy by comparing the visual outcomes after three types of posterior lamellar keratoplasty surgeries Descemet Membrane Endothelial Keratoplasty DMEK, Descemet Stripping Automated Endothelial Keratoplasty DSAEK, and ultra-thin DSAEK UT-DSAEK. This observational cohort study aims to understand how visual acuity and other eye health measures change over time after these surgeries. Participants have had one of the three types of corneal transplant surgeries, where diseased layers of the cornea are replaced with donor tissue of varying thickness and preparation methods. The study compares these groups based on the thickness of the graft used and surgical technique. Data collection involves monitoring outcomes following these procedures performed between 2012 and 2030. During the study, participants will have their best spectacle-corrected visual acuity measured at several timepoints day 8, day 15, 1 month, 3 months, 6 months, 1 year, and yearly up to 10 years after surgery. Additional assessments include endothelial cell density, central corneal thickness, and tracking any post-operative complications during the same follow-up schedule. This long-term monitoring will help identify factors that predict outcomes after these surgeries.

Prognosis of Posterior Lamellar Keratoplasty