Actively Recruiting
Prognostic Impact of Imaging Parameters in Patients With Primary Mitral Insufficiency by Prolapse (COHORTE-IM)
Led by Lille Catholic University · Updated on 2024-03-26
400
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
Sponsors
L
Lille Catholic University
Lead Sponsor
U
University Hospital, Lille
Collaborating Sponsor
AI-Summary
What this Trial Is About
Degenerative mitral insufficiency secondary to valve prolapse is the most common valve disease in Western countries. In the absence of specific treatment, it spontaneously progresses to heart failure and death when it is severe. Surgical mitral valve repair (or mitral plastic surgery) is the preferred treatment for primary mitral insufficiency by prolapse in case of severe leakage if associated with clinical and/or echocardiographic markers of poor prognosis (i.e., with high risk of morbi-mortality during their follow-up). It is therefore essential to refine the risk stratification of these patients in order to identify at-risk patients who should potentially benefit earlier from invasive care (cardiac surgery), or conversely, close monitoring. A number of echocardiographic and MRI parameters may have been associated with a poorer prognosis. A cohort of patients with primary mitral insufficiency (MI) will be followed to study the relationships of a set of factors to patient prognosis.
CONDITIONS
Official Title
Prognostic Impact of Imaging Parameters in Patients With Primary Mitral Insufficiency by Prolapse (COHORTE-IM)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any patient with primary mitral insufficiency by prolapse (any grade) diagnosed by Trans-Thoracic Echocardiography (TTE)
- Diagnosis between November 2010 and April 2019 for retrospective cohort
- Diagnosis between May 2019 and May 2024 for prospective cohort
- No previous surgery of the mitral valve before the first ultrasound
- Adults
- Patient informed and not opposed to use of medical record data
You will not qualify if you...
- Secondary mitral insufficiency
- Primary mitral insufficiency without valve prolapse
- Active endocarditis
- Patient's refusal to participate in the study
- Patient under guardianship or curatorship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lille Catholic Hospitals
Lomme, Nord, France, 59462
Actively Recruiting
Research Team
M
Marie Paule LEBITASY, Md
CONTACT
A
Audrey TOIA, CRA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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