Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs.
W J Wolters, H F Duncan, P L Tomson...
https://pubmed.ncbi.nlm.nih.gov/28776717Actively Recruiting
Age: 18Years - 50Years
All Genders
Healthy Volunteers
ID05816525
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
Led by University of Helsinki · Updated on 2026-04-22
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to study how the condition of a tooth before treatment affects the outcome of partially removing decayed tissue in adult teeth. The main questions are whether preoperative symptoms and the depth of the decay influence the success of the treatment. The study will involve 100 adults with deep carious lesions, focusing on those with mild or reversible pulpitis, to better understand treatment results over time. Participants will undergo partial removal of decayed tissue, where decay is selectively removed from the tooth while preserving healthy tissue. The procedure involves removing decay around the edges of the cavity and selectively removing softened dentin near the pulp, followed by restoration with glass-ionomer cement. After 12 months, if the tooth shows no symptoms and passes sensitivity tests, a final restoration with composite resin is applied. During the study, participants will complete a questionnaire about symptoms 7 days after treatment, including pain assessment using a visual scale. The treated teeth will be monitored for 12 to 24 months with clinical and radiographic evaluations to assess treatment success. The research will track the tooth's condition and response to treatment over time, supported by the University of Helsinki.
CONDITIONS
Brief Title
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
Who Can Participate
Age: 18Years - 50Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- The patient communicates in Finnish or English
- Has a deep primary or secondary carious lesion in 1st or 2nd premolar or molar on occlusal or proximal surface extending to the deepest quarter of dentine
- Symptoms are absent or no more severe than reversible (mild) pulpitis
- Pulp responds to electric pulp testing and cold testing
- Periodontal stage of the tooth is I or II
- If multiple teeth qualify, the one with the deepest lesion and/or most severe symptoms is chosen
You will not qualify if you...
- General medical conditions increasing risk of odontogenic infection complications
- Pregnancy or breastfeeding
- Mental retardation or memory disorder
- Carious lesion extends to more than three surfaces or both proximal surfaces
- Previous fillings deeper than outer third of dentine, larger than Class I or II, not restricted to enamel, or with secondary/residual caries
- Tooth is not restorable
- Periapical changes visible on radiograph
- Sensitivity to percussion, swelling, sinus tract, increased mobility, or resorption
- Furcal lesion more severe than Class I
- Ongoing orthodontic treatment
- Declines to sign written consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Partial Removal of Carious Tissue
Duration - Single treatment day
Participants undergo partial removal of carious tissue with selective excavation to the soft dentin, followed by restoration with high-viscosity glass-ionomer cement.
1 visit (in-person)
Follow-up after Partial Removal
Duration - 7 days
Participants are monitored for symptoms and pain severity 7 days after treatment.
1 follow-up visit (in-person) at 7 days post-treatment
Follow-up Monitoring
Duration - 12 to 24 months
Participants are observed for clinical and radiographic success over 12 to 24 months after treatment.
Periodic visits during follow-up as scheduled by the study
Final Restoration
Duration - Single treatment day after 12 months follow-up
If the tooth is asymptomatic and healthy after follow-up, participants receive a final composite resin restoration with partial removal of glass ionomer cement.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Western Uusimaa Wellbeing Services County
Espoo, Finland
Actively Recruiting
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Research Team
K
Katri Croft, DDS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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