Actively Recruiting
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
Led by University of Helsinki · Updated on 2026-04-22
100
Participants Needed
1
Research Sites
245 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults. The main questions the study aims to answer are: * Do preoperative symptoms affect the outcome? * Does the depth of the carious lesion affect the outcome? One hundred participants will be recruited. Patients who meet the eligibility criteria will be asked to give their informed consent to participate in the study. Partial carious tissue removal will be performed regardless of participation in the study because selective carious tissue removal is the standard treatment of choice for a vital tooth with a deep carious lesion according to the Finnish national treatment guidelines. Participants will be asked to fill in a questionnaire regarding symptoms 7 days post-treatment. The teeth will then be followed up for 12-24 months. The null hypothesis is that there is no difference in the success between i) deep and extremely deep carious lesions and ii) initial and mild pulpitis.
CONDITIONS
Official Title
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient communicates in Finnish or English
- Deep primary or secondary cavity in first or second premolar or molar on occlusal or proximal surface reaching deepest quarter of dentine
- Symptoms are absent or no worse than reversible mild pulpitis
- Pulp responds to electric pulp and cold testing
- Tooth periodontal stage is I or II
- If multiple teeth qualify, the tooth with deepest lesion or most severe symptoms is chosen
You will not qualify if you...
- Medical conditions increasing risk of infection complications
- Pregnancy or breastfeeding
- Mental retardation or memory disorder
- Carious lesion extends to more than three surfaces or both proximal surfaces
- Tooth has previous fillings deeper than outer third of dentine or larger than Class I or II or with secondary caries
- Tooth is not restorable
- Radiographic signs of periapical changes
- Tooth sensitivity to percussion, swelling, sinus tract, increased mobility, or resorption
- Furcal lesion more severe than Class I
- Ongoing orthodontic treatment
- Declines to sign written consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Western Uusimaa Wellbeing Services County
Espoo, Finland
Actively Recruiting
Research Team
K
Katri Croft, DDS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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