Actively Recruiting

Age: 18Years +
All Genders
NCT06182657

The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC

Led by Jiangxi Provincial Cancer Hospital · Updated on 2024-02-08

300

Participants Needed

1

Research Sites

286 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to explore the prognostic value of pathological remission after one cycle of induction chemotherapy in locally advanced nasopharyngeal carcinoma, and the change of immune micro-environment after one cycle induction chemotherapy, including the density of immune cells infiltration and tertiary lymphoid structures.

CONDITIONS

Official Title

The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to sign informed consent
  • Age greater than 18 years at time of study entry
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Histological confirmation of nasopharyngeal carcinoma (EBER positive or negative)
  • Locally advanced nasopharyngeal carcinoma, UICC stage III-IVa
  • Willingness and ability to comply with the protocol including treatment, scheduled visits, examinations, and follow-up
Not Eligible

You will not qualify if you...

  • Concurrent enrollment in another clinical study unless observational or during follow-up of an interventional study
  • Presence of distant metastases
  • Prior systemic anti-cancer therapy for locally advanced nasopharyngeal carcinoma
  • History of another primary malignancy
  • Female patients who are pregnant
  • Known allergy or hypersensitivity to any drugs
  • Investigator judgment that the patient is unsuitable or unlikely to comply with study procedures and requirements

AI-Screening

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Trial Site Locations

Total: 1 location

1

Jingao Li

Nanchang, Jiangxi, China, 330029

Actively Recruiting

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Research Team

J

Jingao Li, PhD

CONTACT

T

Tianzhu Lu, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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