Actively Recruiting
Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients
Led by Guowei Tu · Updated on 2026-02-24
1491
Participants Needed
2
Research Sites
170 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project aims to detect novel biomarkers from preoperative and early postoperative serum and urine samples of patients to screen and analyze the risk factors for predicting adverse postoperative renal outcomes in high-risk patients in cardiac surgery.
CONDITIONS
Official Title
Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults scheduled for elective open chest cardiac surgery
- Patients undergoing surgery with cardiopulmonary bypass (CPB) must have at least one AKI risk factor
- Patients undergoing surgery without CPB must have at least two AKI risk factors
- AKI risk factors include age over 70 years, estimated glomerular filtration rate (eGFR) between 30 and 60 mL/min/1.73 m2, diabetes mellitus, proteinuria, history of congestive heart failure within the past year, left ventricular ejection fraction of 40% or lower, prior cardiac surgery, combined coronary artery bypass and valve procedure, urgent procedure, or use of preoperative intra-aortic balloon pump
You will not qualify if you...
- Pre-existing chronic kidney disease with eGFR less than 30 mL/min/1.73 m2
- Previous renal replacement therapy before cardiac surgery
- Acute kidney injury present at screening
- History of kidney transplant or other kidney diseases
- Known pregnancy
- Multiple operations during the same hospital stay
- Being in a moribund state with an expected death within 48 hours
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Zhongshan hospital, Fudan university
Shanghai, Shanghai Municipality, China, 200030
Not Yet Recruiting
2
Zhongshan hospital
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
G
Guo wei Tu, MD
CONTACT
Y
Ying Su, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here