Actively Recruiting

Age: 18Years +
All Genders
NCT04437628

Prognostic Value Of Short-Term Follow-up Biomarkers After Discharge In hOspitalized Patients With Acute Heart Failure

Led by Wonju Severance Christian Hospital · Updated on 2024-09-19

1500

Participants Needed

1

Research Sites

256 weeks

Total Duration

On this page

Sponsors

W

Wonju Severance Christian Hospital

Lead Sponsor

R

Roche diagnostics Korea

Collaborating Sponsor

AI-Summary

What this Trial Is About

Several surrogate biomarkers including natriuretic peptide(NP), and growth differentiation factor-15(GDF-15) and ST2 has prognostic significance in heart failure(HF), and reductions in its value may predict clinical improvement. However, there are limited data regarding the prognostic value of these biomarkers during short-term follow-up after discharge in acute decompensated heart failure. The purpose of this study is to evaluate the prognostic value of short-term follow-up surrogate biomarkers for predicting prognosis of hospitalized patients with acute decompensated heart failure.

CONDITIONS

Official Title

Prognostic Value Of Short-Term Follow-up Biomarkers After Discharge In hOspitalized Patients With Acute Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of heart failure with either reduced ejection fraction (EF < 40%) and symptoms/signs of heart failure
  • Or diagnosis of heart failure with preserved ejection fraction (EF 64 40%) including symptoms/signs of heart failure
  • Elevated natriuretic peptide levels (BNP > 100 pg/ml and/or NT-proBNP > 300 pg/ml) for preserved EF patients
  • Presence of structural heart disease (left atrial volume index 64 34 mL/m2, left atrial dimension 64 50 mm, or posterior/septal wall thickness 64 11 mm) for preserved EF patients
Not Eligible

You will not qualify if you...

  • Severe condition limiting life expectancy to less than 3 months
  • Not willing or unable to be contacted by telephone at the end of the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Yonsei University Wonju College of Medicine

Wŏnju, Gangwondo, South Korea, 26426

Actively Recruiting

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Research Team

D

Dong-Hyuk Cho, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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