Actively Recruiting

Phase Not Applicable
FEMALE
Healthy Volunteers
NCT06580327

Programmed Intermittent Epidural Bolus Compared With Continuous Infusion in Multiparous Women

Led by Holy Family Hospital, Nazareth, Israel · Updated on 2026-04-13

186

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in multiparous women compared to continuous epidural infusion. multiparous women will randomly be divided during labor into two groups; study group will receive mix of Bupivacaine and fentanyl once (bolus) every 60 minutes; the control group will receive continuously the same dose during an hour, until delivery.

CONDITIONS

Official Title

Programmed Intermittent Epidural Bolus Compared With Continuous Infusion in Multiparous Women

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Multiparous women
  • Term pregnancy
  • Singleton pregnancy
  • Baby in vertex (head down) position
  • Latent phase of labor with cervical dilation less than 6 cm
  • Request for epidural analgesia
  • Visual Analogue Scale score greater than 40
Not Eligible

You will not qualify if you...

  • Estimated fetal weight over 4.0 kg
  • Intrauterine fetal death
  • Sensitivity to study drugs
  • Anomalous fetus
  • Contraindication to epidural analgesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Holy Family Hospital

Nazareth, Israel, 1641100

Actively Recruiting

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Research Team

R

Raed Salim, MD

CONTACT

A

Asmaa Masri Esmail, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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