Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT00574327

Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry

Led by Midwest Biomedical Research Foundation · Updated on 2023-03-16

3000

Participants Needed

1

Research Sites

1200 weeks

Total Duration

On this page

Sponsors

M

Midwest Biomedical Research Foundation

Lead Sponsor

K

Kansas City Veteran Affairs Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to determine or evaluate the risk factors such as smoking, family history etc. that cause esophageal cancer and to determine the genetic changes that lead to esophageal cancer. The investigators hypothesis is that systematic collection of data on the natural history of GERD and BE patients and risk factors for development of BE in patients with chronic GERD and progression of BE to dysplasia and adenocarcinoma will provide useful information to develop a decision model for risk stratification and risk reduction strategies in these patients. As of March 17, 2011, 585 patients have consented at the Kansas City VA Medical Center.

CONDITIONS

Official Title

Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Kansas City VA patients with confirmed Barrett's esophagus with or without dysplasia
  • Patients with gastroesophageal reflux disease
  • Patients undergoing endoscopy for other reasons such as anemia, weight loss, or diarrhea but without GERD or Barrett's esophagus
  • Eligible for care at the Kansas City VA Hospital
Not Eligible

You will not qualify if you...

  • Uncontrolled significant comorbidities like cardiovascular, pulmonary, renal, hepatic, or metabolic diseases
  • Use of anticoagulation that increases biopsy risk
  • Inability to provide medical history
  • Diagnosis of dyspepsia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Veterans Affairs Medical Center

Kansas City, Missouri, United States, 64128

Actively Recruiting

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Research Team

A

April D Higbee, RN, BSN

CONTACT

C

Carly Campbell, MS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry | DecenTrialz