Actively Recruiting
Progression of Metabolic Syndrome Components During Pregnancy
Led by University Ghent · Updated on 2024-07-08
526
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
Sponsors
U
University Ghent
Lead Sponsor
F
Flemish Interuniversity Council (VLIR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this cohort study is to investigate the underlying risk factors to develop metabolic syndrome (MetS) during pregnancy, and the associations of MetS and its indicators with birth outcomes in southwest Ethiopia. The study population consists of low-risk pregnant ladies in their first antenatal care visit (ANC), from Jimma Medical center. The main question\[s\] it aims to answer are: i) How do MetS components progress during pregnancy, and what are the underlying risk factors? ii) What is the association between MetS components during early- and late pregnancy and adverse pregnancy outcomes? iii) What is the knowledge, attitude and practices of women toward dietary habits, food taboos, and cultural beliefs during pregnancy? The study population consists of low-risk pregnant ladies in their first trimester (\<15 weeks of pregnancy) in their first antenatal care visit (ANC) who will be followed up until one-month postpartum. Enrolled women will be assessed four times: at enrolment ≤15 weeks of pregnancy, mid-pregnancy (at 24 weeks), and late pregnancy (at 36 weeks), and within two weeks post-partum for: 1. Sociodemographic data 2. Dietary intake 3. Biochemical analyses 4. Maternal anthropometry: 5. Body composition in a subsample. 6. Knowledge, attitudes and practices of dietary practices during pregnancy 7. Pregnancy and birth outcomes: During the final visit, new born babies will be assessed for Apgar score, weight, length, and head circumference. The mother will be examined for general health and mode of delivery.
CONDITIONS
Official Title
Progression of Metabolic Syndrome Components During Pregnancy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy pregnant women attending their first antenatal care visit before 15 weeks of pregnancy
- Women aged between 18 and 45 years
- Women with or without at least one of the 5 metabolic syndrome components
- For the exposed group, women with abdominal obesity (waist circumference ≥ 2 SD for gestational age or BMI >30 kg/m2), or raised triglycerides (>1.70 mmol/l), or low HDL cholesterol (<1.29 mmol/l), or raised blood pressure (systolic >130 mm Hg or diastolic >85 mm Hg), or raised plasma glucose (>5.6 mmol/l)
You will not qualify if you...
- Women with chronic hypertension requiring medication
- Women with diabetes under medication
- Women with severe chronic illness
- Women with HIV taking antiretroviral therapy (ART)
- Women younger than 18 years
- Women planning to move outside the study area during the study period
- Women unwilling to follow up during the study
- Women with ultrasound confirmed twin pregnancy
- Women with fetal congenital anomaly or fetal death in utero
AI-Screening
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Trial Site Locations
Total: 1 location
1
Jimma University Medical Center
Jimma, Ethiopia
Actively Recruiting
Research Team
S
Souheila Abbeddou, MSc. PhD
CONTACT
A
Abonesh Taye Kumsa, MSc.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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