Actively Recruiting

Phase Not Applicable
Age: 40Years - 75Years
All Genders
NCT05918380

Project 3: ACHIEVE- CHD

Led by University Hospitals Cleveland Medical Center · Updated on 2025-07-14

500

Participants Needed

1

Research Sites

228 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions, hypertension (HTN, Project 1), heart failure (HF, Project 2) and coronary heart disease (CHD, Project 3), which drive downstream lifespan inequality. All three projects will involve the use of Community Health Workers (CHWs) to deliver an evidence-based practice intervention program called PAL2. All three projects will also utilize the PAL2 Implementation Intervention (PAL2-II), which is a set of structured training and evaluation strategies designed to optimize CHW competence and adherence (i.e., fidelity) to the PAL2 intervention program. The present study is Project 3 of the ACHIEVE GREATER Center.

CONDITIONS

Official Title

Project 3: ACHIEVE- CHD

Who Can Participate

Age: 40Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 40 to 75 years of age
  • Self-identified as Black or African American
  • Residence in the Cleveland Metro Area
  • At least two risk factors including BMI over 30 mg/dL, history of smoking, elevated blood pressure (SBP >140 or DBP >80 mmHg), HbA1c ≥5.7%, or LDL ≥130
  • Able to complete a coronary artery calcium score test
  • Willing and able to provide consent
  • Willing to receive care from a University Hospitals provider
  • Currently insured for standard care procedures
Not Eligible

You will not qualify if you...

  • Established documented cardiovascular disease such as coronary artery disease, peripheral artery disease, myocardial infarction, or stroke
  • Systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg
  • Lung disease requiring supplemental oxygen therapy
  • Currently receiving treatment for cancer
  • Pregnant or nursing mothers

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106

Actively Recruiting

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Research Team

S

Sanjay Rajagopalan, MD

CONTACT

H

Heidi Osborne

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

2

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