Project Gnosis Effects of an 8-week Tai Chi Program on Brain, Body, and Social Health in Older Adults with or without Mild Cognitive Impairment

What this Trial Is About

Researchers are studying older adults with Mild Cognitive Impairment MCI and sarcopenia to understand how Tai Chi, a mind-body exercise, may influence cognitive function, mood, and physical health. The study aims to explore how heart rate variability and brain activity relate to cognitive function and how pain interference and social isolation affect cognition. Additionally, it examines the roles of muscle loss and obesity in these relationships and seeks to predict cognitive outcomes based on these factors. Participants will engage in an 8-week Tai Chi program based on the Harvard Medical School Guide to Tai Chi. The program includes weekly 75-minute in-person classes led by the principal investigator, supported by a workbook and video series for home practice. Sessions introduce Tai Chi principles, warm-up exercises, Tai Chi movements, and cool-down exercises. Virtual live sessions may be offered for those unable to attend in person. During the study, participants cognitive function will be assessed using tests such as the Stroop Color-Word Interference Test and Semantic Fluency Test. Researchers will also monitor processing speed, pain interference, social isolation, positive mood, sense of meaning, heart rate variability, and brain activity from enrollment through the end of the 8-week intervention. This comprehensive assessment will help understand the effects of Tai Chi on neurophysical and psychosocial health in older adults with or without MCI.

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment