Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
Healthy Volunteers
NCT06828926

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

Led by Ohio University · Updated on 2025-02-17

50

Participants Needed

1

Research Sites

54 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance. Tai Chi, a mind-body exercise, is recommended for managing MCI as it supports cognitive function, mood, and physical health. The investigators' first goal is to characterize the correlation of heart rate variability and cortical activity on cognitive function and the psychosocial correlates of pain interference and social isolation on cognitive function at baseline and post-intervention (8 weeks of Tai Chi). The second goal is to explain the role of sarcopenia and obesity in the relationship between pain interference and cognitive function. The investigators also want to examine the index of the predictive capacity regarding sarcopenia and obesity on cognitive function outcomes.

CONDITIONS

Official Title

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants who are 60 years old or older
  • Ability to stand independently without an assistive device for at least 20 minutes
  • Participants with Mild Cognitive Impairment (MCI) or age- and gender-matched healthy controls
  • MCI classified by a Montreal Cognitive Assessment score between >18 and 6
Not Eligible

You will not qualify if you...

  • Significant uncontrolled medication, cardiovascular, respiratory, or metabolic symptoms
  • Symptoms of hypotension or hypoglycemia related to intensive treatment
  • Significant uncontrolled sleep apnea or sleep-disordered breathing
  • Currently practicing Tai Chi or practiced Tai Chi within the last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Ohio University

Athens, Ohio, United States, 45701

Actively Recruiting

Loading map...

Research Team

N

Nicholas Karayannis, MPT, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here