Actively Recruiting

All Genders
Healthy Volunteers
NCT06372106

Project Mountain - Comparing SpO2 and SaO2 for Accuracy

Led by Philips Clinical & Medical Affairs Global · Updated on 2025-04-02

560

Participants Needed

5

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main goal of this study is to look at the performance of the neonatal, infant, and pediatric Philips SpO2 sensors with the Philips FAST Pulse Oximetry technology. Oxygen saturation measurements (SpO2) will be obtained via pulse oximetry and invasive arterial oxygen measurements (SaO2) will be obtained via arterial blood samples as part of your clinical care and assessed by co-oximetry. The study will aim to enroll a diverse population to help us understand the impact of skin pigmentation.

CONDITIONS

Official Title

Project Mountain - Comparing SpO2 and SaO2 for Accuracy

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject aged 18 years or older or parent/legal guardian of subject aged less than 18 years, willing and able to understand and provide written informed consent/assent.
  • Weight and/or age within intended use of at least one SpO2 sensor under test at time of enrollment.
  • Willing and able to wear study devices in addition to SoC devices and during SoC procedures.
  • In-patient within a neonatal or pediatric intensive care unit (e.g. NICU, PICU, PCICU).
  • Has arterial access and ability to have arterial blood samples drawn as part of their SoC and analyzed by CO-Oximetry.
Not Eligible

You will not qualify if you...

  • Known pregnancy or lactating females (self-reported)
  • Injury, wounds, physical malformation, hyperkeratosis, or compromised/non-intact skin at sensor application site (i.e. fingers, toes, hands, feet, ears, nasal ala). Note: Certain malformations may be allowed if determined it would not affect application of sensor with the pulse oximetry system.
  • Self-reported severe contact allergies to standard adhesives or other materials found in pulse oximetry sensors. Note: Subject may be considered eligible if subject can wear non-adhesive sensor.
  • Unwillingness or inability to remove nail polish or artificial nails from sensor application site.
  • Nail fungus on sensor application site.
  • Wearing and unable to remove jewelry from sensor application site.
  • Dye injection within 48 hours of enrollment.
  • Known dysfunctional hemoglobin levels (COHb >3%, MetHb >2%, and ctHb <10g/dl)
  • Undergoing phototherapy for neonatal hyperbilirubinemia during arterial blood sampling

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Phoenix Children's

Phoenix, Arizona, United States, 85016

Actively Recruiting

2

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68114

Actively Recruiting

3

Duke University Medical Center

Durham, North Carolina, United States, 27710

Actively Recruiting

4

Medical University of South Carolina

Charleston, South Carolina, United States, 29425

Actively Recruiting

5

Baylor College of Medicine

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

K

Kelsey Rothwell

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Project Mountain - Comparing SpO2 and SaO2 for Accuracy | DecenTrialz