Actively Recruiting
Project neuroARTEMIS
Led by Wake Forest University Health Sciences · Updated on 2025-09-11
189
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
F
Florida International University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to understand how chronic stress affects the way our brain and immune systems function, and in turn how this affects the way people feel, think, and behave. By learning more about how these processes work, the hope is to be able to develop better treatments to help with problems like depression and substance use. This study is intended for individuals that are HIV positive, currently taking prescription antiretroviral medications, and use stimulants. Through this intervention, the aim is to determine if this positive affect intervention can lead to reductions in stimulant use and depressed mood.
CONDITIONS
Official Title
Project neuroARTEMIS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 59 years
- Weekly stimulant use reported in the past month or a score of 4 or higher on substance use screening
- Confirmed diagnosis of HIV
- Currently taking daily oral antiretroviral therapy (ART) medication
- Fluent and literate in English
You will not qualify if you...
- Acute brain infections such as neurosyphilis or toxoplasmosis
- Acutely symptomatic bipolar I disorder or psychotic disorder
- Currently prescribed immunomodulatory medications or other immunotherapy
- Any contraindications for MRI scanning
- On antidepressant medication regimen for at least 2 months if applicable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States, 27101
Actively Recruiting
Research Team
C
Christina S Meade, PhD
CONTACT
S
Sheri L Towe, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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