Actively Recruiting
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Led by University of Pittsburgh · Updated on 2025-12-10
180
Participants Needed
2
Research Sites
386 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
B
Brown University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and psychosocial health complications. Although our recently published data suggest that youth with these conditions may have relative deficits in neurocognitive functioning, particularly working memory, understanding of how these processes and their neural correlates are related to change and stability in eating and weight-related outcomes over time is limited, thereby impeding development of targeted, optimally timed interventions. The present study aims to assess prospective associations between general and food-specific executive functioning and underlying neural substrates, and eating and weight outcomes among children at varying levels of risk overweight/obesity and eating disorders, which will help guide research efforts towards the development of effective prevention and intervention strategies.
CONDITIONS
Official Title
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Not currently taking any medications known to affect weight or appetite
- No current or past medical or psychiatric conditions significantly affecting eating or weight except binge eating disorder
- General intellectual functioning in the low average range or higher
- No conditions affecting executive functioning such as recent concussion or traumatic brain injury
- Fluent in English and able to read and understand study materials
- Not currently pregnant
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of PIttsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
2
Weight Control & Diabetes Research Center
Providence, Rhode Island, United States, 02903
Active, Not Recruiting
Research Team
E
Erin Stalvey, B.S.
CONTACT
C
Chloe Hudson, B.S.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
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