Actively Recruiting
Prolonged Exposure for Swedish Immigrants
Led by Karolinska Institutet · Updated on 2025-04-09
100
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare therapist-guided internet delivered prolonged exposure (I-PE) in simple english to a waiting list condition for immigrants in Sweden diagnosed with post-traumatic stress disorder (PTSD). The main objectives are to establish feasibility and preliminary efficacy of I-PE for immigrants with PTSD in a single-blind, parallel-group superiority Randomized Controlled Trial (N=100) comparing I-PE with a waiting-list condition, starting with a nested pilot (N=30) to ensure feasible and acceptable recruitment and treatment strategies. Study participants will be randomly assigned to either eight weeks of I-PE or a waiting-list for the same amount of time on a 1:1 ratio without restriction. Feasibility and acceptability data will be reported including recruitment rate, sample demographics, data attrition, treatment adherence and a detailed dropout analysis. A preliminary investigation of the within-group effect size will also be conducted. Recruitment is designed to be broadly inclusive with minimal exclusion criteria.
CONDITIONS
Official Title
Prolonged Exposure for Swedish Immigrants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Current primary diagnosis of PTSD based on DSM-5 criteria
- At least 18 years old
- Able to read and write in English
- Immigrant residing in Sweden
- Able to provide digital informed consent
- Daily access to a computer or internet-connected device
You will not qualify if you...
- PTSD is not the primary treatment concern
- Started or changed psychotropic medication within 4 weeks before treatment
- Serious mental health symptoms like mania, psychosis, substance use disorders, or current suicide risk needing immediate care
- Currently receiving trauma-focused CBT or Eye Movement Desensitization and Reprocessing therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Solna, Sweden
Actively Recruiting
Research Team
M
Maria Bragesjö, PhD
CONTACT
O
Olof Molander, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here