Effectiveness of Combined Dextrose and Lidocaine Prolotherapy at Lumbar Acupuncture Points for Chronic Non-specific Low Back Pain

What this Trial Is About

Chronic non-specific low back pain CNSLBP is a common and disabling condition that often does not respond well to standard treatments like medications and physical therapy. This research evaluates whether combining prolotherapy using a 15% dextrose solution with 1% lidocaine injections at specific lumbar acupuncture points is more effective than using lidocaine injections alone. The trial is a single-blind randomized controlled study aiming to improve pain and function in adults with CNSLBP. Participants will be randomly assigned to one of two groups one receiving injections of dextrose plus lidocaine, and the other receiving lidocaine only. Each participant will undergo up to 15 ultrasound-guided injections at standardized acupuncture points in the lumbar region during three sessions spaced over four weeks. The study uses precise injection techniques and standardized locations to assess the added value of dextrose in prolotherapy. Throughout the study, participants will complete assessments of pain severity, disability, and physical function using various validated tools at baseline and multiple follow-up points up to 90 days post-treatment. Safety will be monitored by recording any injection-related side effects. The study will provide detailed information on the effectiveness and tolerability of the treatments, with total participation lasting several months including treatment and follow-up visits.

Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)