Actively Recruiting

Age: 18Years +
All Genders
NCT07227961

PROMIS and Mobility Evaluation in Sarcoma Patients

Led by University of Calgary · Updated on 2025-11-13

800

Participants Needed

4

Research Sites

287 weeks

Total Duration

On this page

Sponsors

U

University of Calgary

Lead Sponsor

U

University of Toronto

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this is to validate the Patient-Reported Outcomes Measurement Information System (PROMIS) in sarcoma patients undergoing surgery, and to evaluate a novel smartphone app for collecting mobility data. The goals of the study include to: 1. Validate PROMIS as a patient outcome measure in sarcoma 2. Assess the effectiveness of a novel app for administering questionnaires and collecting mobility metrics 3. Compare PROMIS scores and mobility metrics to better evaluate recovery trajectories after surgery Participants will complete PROMIS questionnaires at regularly scheduled intervals using the smartphone app. Questionnaires will be completed pre-operatively and at 6 weeks, 12 weeks, 6 months, and 12 months post-operatively. Additionally, the app will passively track mobility metrics such as daily step count, stairs climbed, and gait parameters to compare with PROMIS scores.

CONDITIONS

Official Title

PROMIS and Mobility Evaluation in Sarcoma Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of bone sarcoma, soft tissue sarcoma, or giant cell tumor of bone
  • Tumor located in the pelvis, lower extremities, or upper extremities
  • Primary or recurrent disease
  • Scheduled for operative tumor resection including limb salvage surgery or amputation
  • Has an iPhone or Android phone
  • Speaks English
Not Eligible

You will not qualify if you...

  • Metastatic bone tumor
  • Diagnosis of atypical lipomatous tumor or dermatofibrosarcoma protuberans
  • Currently pregnant or planning pregnancy within 6 months
  • Unwilling or unable to attend follow-up evaluations
  • Cognitive or communication barriers that prevent completing questionnaires

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Mayo Clinic

Phoenix, Arizona, United States, 85054

Not Yet Recruiting

2

Mayo Clinic

Rochester, Minnesota, United States, 55905

Not Yet Recruiting

3

Foothills Medical Centre, Arthur J Child Comprehensive Cancer Centre, University of Calgary

Calgary, Alberta, Canada, T2N 2T9

Actively Recruiting

4

Mount Sinai Hospital, University of Toronto

Toronto, Ontario, Canada, M5G 1X5

Not Yet Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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