Actively Recruiting
Promoting Early Intervention Timing and Attention to Language
Led by University of California, Los Angeles · Updated on 2026-03-31
140
Participants Needed
2
Research Sites
187 weeks
Total Duration
On this page
Sponsors
U
University of California, Los Angeles
Lead Sponsor
U
University of Massachusetts, Worcester
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of having an older sibling with autism) on communication and language outcomes at 24 months. Results of this study will determine when (9 vs 12 vs 15 months), and based on which measures (brain, language, or their combination) to augment parental support with a specialized parent-mediated coaching intervention for optimal outcomes on communication and language at 24 months. Children will be recruited at 6-8 months of age and will begin with entry assessments. All children will first begin with the MONITOR condition (using Ages \& Stages Questionnaire (ASQ-3) and activity cards. Then when the child is 9 months, they will be randomized to continue with MONITOR condition or COACH condition (i.e. JASPER Babble) after second set of assessments. There are a total of 6 assessment timepoints (6-8 months of age, 9 months of age, 12 months of age, 15 months of age, 18 months of age, and 24 months of age). At time points of 9months and 12 months, the child will be randomized to COACH or MONITOR conditions. Once the child is randomized to COACH condition, they will continue with that condition until they terminate the study at 24 months. At the 15 months timepoint, there will no longer be a randomization. Children that were in the MONITOR condition will change to the COACH condition until they terminate the study.
CONDITIONS
Official Title
Promoting Early Intervention Timing and Attention to Language
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infants aged 6 to 8 months who have an older sibling with autism spectrum disorder
- Both male and female infants are eligible
- Families with income under the very low income level defined by the Los Angeles Department of Housing and Community Development Division of Housing Policy Agreement
You will not qualify if you...
- Infants with seizures not stable on anti-seizure medication
- Infants expected to have surgery within the next year
- Infants with physical disorders, co-morbid syndromes or diseases
- Infants with sensory or motor impairments such as vision or hearing loss
- Infants with genetic syndromes such as Down Syndrome
- Infants born prematurely before 34 weeks gestational age
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
UCLA
Los Angeles, California, United States, 90095
Actively Recruiting
2
University of Massachusetts Medical Center
Worcester, Massachusetts, United States, 01655-0002
Actively Recruiting
Research Team
C
Connie Kasari, PhD
CONTACT
C
Consuelo Garcia, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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