Study of Electrical Stimulation Therapy to Help Nerve Healing After Surgery for Arm Nerve Injury

What this Trial Is About

This research aims to evaluate the use of a new electrical stimulation therapy to help heal nerve injuries in the arm after surgery. The study focuses on people with peripheral nerve injuries who are undergoing surgical repair, including nerve transfer, primary repair, or nerve grafting. Researchers want to see if a brief electrical stimulation during surgery can improve nerve healing and functional recovery compared to standard care alone. Participants will be randomly assigned to one of two groups. One group will receive the usual surgical treatment for their nerve injury, while the other group will receive the same surgery plus a single 10-minute dose of electrical stimulation to the injured nerve during the procedure. The electrical stimulation is delivered using a single-use medical device called the Checkpoint BEST System. During the study, participants will have assessments before surgery and at multiple times afterward, up to 18 months. These include tests of motor recovery, grip strength, pinch strength, sensation, pain interference, and arm function questionnaires. Electromyography and motor unit number estimation tests will also be done at several points. The research team will monitor recovery over time to understand how the electrical stimulation may affect healing and function after nerve surgery.

Promoting Healing of Injured Nerves With Electrical Stimulation Therapy