Actively Recruiting

Phase Not Applicable
Age: 8Years - 25Years
All Genders
NCT06555939

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Led by Boston Children's Hospital · Updated on 2026-05-05

25

Participants Needed

1

Research Sites

253 weeks

Total Duration

On this page

Sponsors

B

Boston Children's Hospital

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a resilience-promoting intervention through a Collaborative Care Model. The primary goal is to determine with the resilience intervention (PRISM) is feasible and acceptable for adolescents and young adults with SCD. Exploratory outcomes include whether this intervention improves depression, anxiety, and pain interference.

CONDITIONS

Official Title

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Who Can Participate

Age: 8Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 8 to 25 years at baseline
  • Diagnosed with Sickle Cell Disease (HbSS, HbSC, HbS-Beta Thalassemia, or related hemoglobinopathies)
  • Receiving medical care at the DFCI/BCH Blood Disorders Center
  • Scored above 9 on Patient Health Questionnaire 9-item (PHQ-9) or Generalized Anxiety Disorder (GAD)
  • Able to speak English or Spanish for PRISM sessions
  • Able to read English or Spanish for completing surveys
  • Cognitively able to participate in PRISM sessions and complete questionnaires, as judged by site investigator
  • Willing and able to follow study visit schedule and protocol requirements
Not Eligible

You will not qualify if you...

  • Does not meet the above inclusion criteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

A

Abby Rosenberg, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease | DecenTrialz