Actively Recruiting

Phase Not Applicable
Age: 16Years - 25Years
All Genders
NCT05916651

Promoting Resilience in Youth Through Mindfulness mEditation

Led by Radboud University Medical Center · Updated on 2024-12-13

155

Participants Needed

2

Research Sites

155 weeks

Total Duration

On this page

Sponsors

R

Radboud University Medical Center

Lead Sponsor

D

Donders Centre for Cognitive Neuroimaging

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this randomized controlled trial (RCT) is to assess whether mindfulness training reduces early stage internalizing problems such as anxiety, worrying, and low mood in help-seeking youth. Participants will be randomly assigned to one of two groups: 1) mindfulness + care-as-usual (CAU) or 2) CAU-only. The mindfulness program was developed specifically for youth with internalizing problems. The 8-week training program consists of weekly 2-hour sessions, with mindfulness, yoga, and mindful active movement in each session. In addition, participants are invited to practice at home in between sessions for around 20 minutes per day. Data will be collected at baseline (T0), end-of-treatment (T1) (or 2-3 months after baseline for the CAU-only group), and at 2 months follow-up (T2) and 6 months follow-up (T3). Measurements will include: * Self-report questionnaires (T0, T1, T2, T3) * Psychiatric diagnostic interview (T0, T3) * MRI scans (T0, T1) * Cognitive tasks (T0, T1) The primary outcome parameter is the total number of internalizing problems measured with the Adult Self Report (ASR) at end-of-treatment. The effect of mindfulness training (mindfulness + CAU vs. CAU-only) on internalizing problems at T1 will be assessed using a linear-mixed effects model.

CONDITIONS

Official Title

Promoting Resilience in Youth Through Mindfulness mEditation

Who Can Participate

Age: 16Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Youth between 16 and 25 years of age
  • Provide written informed consent
  • Adequate mastery of Dutch language
Not Eligible

You will not qualify if you...

  • Lifetime diagnosis of severe major depression, bipolar disorder, schizophrenia spectrum disorder, personality disorder, or post-traumatic stress disorder
  • History of major medical illness or neurological illness
  • Participation in a mindfulness programme in the past year
  • Current participation in another intervention study
  • Moderate to severe substance use disorders (mild substance use allowed)
  • Current active suicidality, psychotic symptoms above clinical cut-off, or trauma-related complaints above clinical cut-off for PTSD
  • Diagnosed or suspected mild intellectual disability (estimated IQ below 75)

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Radboud university medical center (Radboudumc)

Nijmegen, Gelderland, Netherlands, 6500 HB

Actively Recruiting

2

Donders Centre for Cognitive Neuroimaging (DCCN)

Nijmegen, Gelderland, Netherlands, 6525 EN

Active, Not Recruiting

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Research Team

G

Guusje Collin, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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