Actively Recruiting
Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?
Led by Montefiore Medical Center · Updated on 2026-02-02
84
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of antibiotics, beginning no more than sixty minutes prior to EVD placement, to the incidence of VRIs in patients who also receive a pre-procedural dose of antibiotics with continued dosing of antibiotics for the duration of the external ventricular drain (EVD). At this time, the duration of prophylactic antibiotic use with antibiotic impregnated EVDs is unknown.
CONDITIONS
Official Title
Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients over the age of 18 years
- Patients diagnosed with subarachnoid hemorrhage, intracerebral hemorrhage, or acute ischemic stroke who need an external ventricular drain (EVD) for treatment
- Patients who may require EVD replacement due to failure and will be re-dosed with antibiotics before catheter exchange
You will not qualify if you...
- Patients who were on antibiotics within the week prior to admission
- Patients with leukopenia (white blood cell count less than 5000) at the start of the study
- Patients who show signs of meningitis, ventriculitis, or other infections at the time of presentation
- Patients who are pregnant or prisoners
- Patients under 18 years of age
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Montefiore Medical Center
The Bronx, New York, United States, 10452
Actively Recruiting
Research Team
D
David C Altschul, MD
CONTACT
G
Genesis Liriano
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here