Actively Recruiting
Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial
Led by University College Dublin · Updated on 2024-10-15
164
Participants Needed
1
Research Sites
131 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn whether giving surfactant through a thin endotracheal catheter to extremely premature babies shortly after birth reduces the number of them who are ventilated in the first 3 days of life. The main question it aims to answer is: Do fewer babies who receive prophylactic thin catheter surfactant under video laryngoscopy shortly after birth go on to be ventilated within 72 hours of birth? Extremely premature babies who are receiving breathing support through a face mask will either: * Receive surfactant through a thin catheter that is inserted into their windpipe (trachea) under video laryngoscopy at or after 5 minutes of life, have the catheter removed immediately, and return to face mask breathing support; or * Continue on face mask breathing support. All babies will be closely watched to see whether they are ventilated for breathing support in the first 72 hours of life.
CONDITIONS
Official Title
Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infants of any sex born before 28 weeks of gestation
- Clinicians plan to provide intensive care
- Consent for their participation provided by parent(s)/guardian(s) before their birth
You will not qualify if you...
- Major congenital anomalies such as upper airway anomaly, diaphragmatic hernia, gastroschisis, exomphalos major, intestinal atresias, open neural tube defect, aneuploidy, or cardiac lesions other than ASD/PFO/VSD/PDA
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
National Maternity Hospital
Dublin, None Selected, Ireland, D02 YH21
Actively Recruiting
Research Team
C
Colm PF O'Donnell, MB PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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