Study of Tranexamic Acid to Lower Blood Loss During Caesarean Delivery

What this Trial Is About

Postpartum hemorrhage is a leading cause of health complications and death among mothers worldwide, accounting for 25% of pregnancy-related deaths. It can happen unexpectedly even without known risk factors. Researchers are studying tranexamic acid, a medication that helps reduce bleeding, to see if it can decrease blood loss when given before cesarean sections alongside other medicines that help contract the uterus. The study compares two groups of women undergoing cesarean delivery. One group receives 1 gram of tranexamic acid diluted in 100 ml of normal saline through an intravenous infusion 10 minutes before the skin incision. The other group receives a placebo infusion of 100 ml normal saline at the same time. This randomized, double-blind study aims to evaluate the impact of tranexamic acid in preventing excessive bleeding during and after surgery. Participants will be monitored from the start of surgery until 24 hours after the cesarean section to measure the amount of blood lost during this period. Researchers will track and compare bleeding between the groups to assess the effectiveness of tranexamic acid. The total participation duration includes the surgery day and the immediate postoperative period for safety and outcome assessments.

Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery.