Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT05358535

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

Led by University of Texas Southwestern Medical Center · Updated on 2026-01-20

200

Participants Needed

1

Research Sites

232 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).

CONDITIONS

Official Title

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older
  • Scheduled for an endoscopic procedure at Clements University Hospital with anesthesia
  • American Society of Anesthesiologists (ASA) classification of 3 or above
  • Ejection fraction test result available
Not Eligible

You will not qualify if you...

  • Known allergies or adverse reactions to propofol, etomidate, their components, or preservatives
  • Patient refusal to participate
  • Clinician refusal to enroll the patient
  • Documented cognitive impairments that prevent the patient from consenting, unless a legal surrogate consents
  • Prisoners, incarcerated individuals, or patients in law enforcement custody
  • Pregnancy or refusal to undergo pregnancy testing as per hospital policy before anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clements University Hospital

Dallas, Texas, United States, 75390

Actively Recruiting

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Research Team

C

Christopher Choi

CONTACT

K

Kapil Anand

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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