Actively Recruiting
PROPULSION SANTE: Inflammometry to Improve the Diagnostic Trajectory in Situations of Suspected Asthma in Children and Adults
Led by Université de Sherbrooke · Updated on 2026-04-30
1500
Participants Needed
3
Research Sites
118 weeks
Total Duration
On this page
Sponsors
U
Université de Sherbrooke
Lead Sponsor
A
AstraZeneca
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this observational study is to assess the relevance of inflammometry (based on the measurement of fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC)) as a tool for prioritizing respiratory diagnostic tests. The study will evaluate the role of inflammometry (FeNO and BEC) in prioritizing diagnostic respiratory tests. It will include patients aged six and older with suspected asthma, referred by non-pulmonologists for diagnostic asthma testing (spirometry or methacholine challenge test) at three hospital centers: Sherbrooke University Hospital Center (CHUS), Sainte-Justine University Hospital Center (CHU Sainte-Justine), and the Montreal Children's Hospital. The hypothesis is that using inflammometry as a prioritization tool would reduce diagnostic delays for high-risk patients with elevated biomarkers. This study could help shorten wait times, relieve congestion in diagnostic testing queues, and improve the diagnostic pathway. Additionally, it would enhance the interpretation of pulmonary function test results by incorporating inflammometry findings, leading to better patient stratification. Patients referred from primary care will undergo pulmonary function testing (spirometry ± methacholine challenge) and, as part of the study: FeNO measurement using a portable device Blood test for eosinophil count Questionnaire on asthma control and quality of life, completed at the visit and at follow-ups at 4, 8, and 12 months
CONDITIONS
Official Title
PROPULSION SANTE: Inflammometry to Improve the Diagnostic Trajectory in Situations of Suspected Asthma in Children and Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- patients age 6 and older
- referred by primary care ofr an asthma diagnostic test (spirometry or methacholine challenge)
You will not qualify if you...
- referred by pulmonologist
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
CHU Sainte-Justine
Montreal, Quebec, Canada, H3T 1C5
Not Yet Recruiting
2
Montreal Children's Hospital
Montreal, Quebec, Canada, H4A 3H9
Not Yet Recruiting
3
CIUSSS de l'Estrie - CHUS
Sherbrooke, Quebec, Canada, J1H 5N4
Actively Recruiting
Research Team
S
Simon Couillard, MD, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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