Actively Recruiting
Prosody Assessment After Right Hemisphere Stroke
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-01-23
150
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Following a right stroke, more than half of the patients present a communication disorder. These disorders can notably concern prosody. Nevertheless, these remain relatively poorly assessed and characterized. Prosodic alterations in comprehension can result in a disruption of social cognition with potentially important consequences in terms of functional outcome and quality of life of patients. In clinical practice, the investigators do not have a tool that allows us to finely assess these disorders. Studies in healthy subjects using a processing algorithm capable of arbitrarily manipulating the pitch dynamics of recorded voices have revealed that there are stable internal representations for prosody processing. Initial pilot results show that this method can be used in a clinical context and can indeed identify and accurately measure perceptual processing deficits in prosody following a right stroke. It is necessary to continue the study of this approach with a larger number of subjects in order to have normative data and validate the diagnostic properties of this approach.
CONDITIONS
Official Title
Prosody Assessment After Right Hemisphere Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Right-handed adults over 18 years of age
- French as mother tongue
- Affiliated or beneficiary of a social security plan
- Signed free, informed, and written consent
- For patients: first clinical episode of right supratentorial stroke confirmed by imaging less than 1 year old
- For controls: no history of stroke and age matched within plus or minus 10 years to patients
You will not qualify if you...
- Score less than 10/15 on the Boston Diagnostic Aphasia Examination command execution test indicating comprehension disorders
- Known dementia
- Illiteracy
- Severe dysarthria
- Psychiatric history requiring hospitalization over two months in a specialized environment
- History of brain injury
- Major visual or auditory perceptual disorder, including hearing loss greater than 40 dB HL
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Assistance Publique - Hôpitaux de Paris, Hôpital Pitié-Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
M
Marie VILLAIN, Ms.
CONTACT
A
Anne BISSERY, Ms.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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