Actively Recruiting

Age: 18Years +
All Genders
NCT04645862

Prospective 4D CTA of BAV Competence

Led by University of Pennsylvania · Updated on 2026-02-06

60

Participants Needed

1

Research Sites

369 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study involves annual 4D CTA imaging of the bicuspid aortic valve for a period of 5 years. CTA is often standard of care for BAV patients, but patients in this study will receive a higher radiation dose with a 4D imaging protocol. There may also be patients enrolled in the study who have a 4D CTA for research purposes when a routine CTA is not required for clinical care.

CONDITIONS

Official Title

Prospective 4D CTA of BAV Competence

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years of age
  • Documented bicuspid aortic valve confirmed by clinical imaging with minimal calcification at enrollment
  • Participant must sign the informed consent form
Not Eligible

You will not qualify if you...

  • Pregnancy confirmed by urine test
  • Renal failure with estimated glomerular filtration rate below 30
  • Known allergy to intravenous contrast unless steroid preparation is used as part of routine clinical care
  • Previous aortic valve replacement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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