Actively Recruiting
Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance
Led by Fondazione Italiana Linfomi - ETS · Updated on 2025-06-29
56
Participants Needed
14
Research Sites
155 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective biological study evaluating the persistence of COVID-19 vaccine and other vaccines' (zoster, diphtheria and tetanus)-induced immunity in a subgroup patient affected by Follicular Lymphoma requiring treatment undergoing frontline induction immuno-chemotherapy and anti-CD20 maintenance within the prospective FIL\_FOLL19 study (NCT05058404). Blood samples from patients will be collected before and at planned timepoints during treatment to evaluate humoral and cellular immunity against SARS-COV-2, VZV, tetanus and diphtheria and T-cell markers characterization.
CONDITIONS
Official Title
Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Enrolled in the FIL_FOLL19 study
- Received at least three doses of COVID-19 vaccine
- Have available information about COVID-19 and other prior vaccinations
- Willing to comply with required blood sample collections for immunity evaluation
- Signed the specific informed consent form
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
Azienda Ospedaliera S.Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico
Avellino, AV, Italy, 83100
Actively Recruiting
2
A.O. SS. Antonio e Biagio e Cesare Arrigo, S.C. Ematologia
Alessandria, IT, Italy
Actively Recruiting
3
Nuovo Ospedale degli Infermi, SSD Ematologia
Biella, IT, Italy
Actively Recruiting
4
ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia
Milan, IT, Italy
Actively Recruiting
5
Ospedale Maggiore Policlinico Fondazione IRCCS Ca' Granda - Ematologia
Milan, IT, Italy
Actively Recruiting
6
A.O.U. Maggiore della Carità di Novara - S.C.D.U. Ematologia
Novara, IT, Italy
Actively Recruiting
7
IRCCS Policlinico San Matteo - Divisione di Ematologia
Pavia, IT, Italy
Actively Recruiting
8
Ospedale Guglielmo da Saliceto - U.O. Ematologia
Piacenza, IT, Italy
Actively Recruiting
9
A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia U
Torino, IT, Italy
Actively Recruiting
10
A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia
Torino, IT, Italy
Actively Recruiting
11
ASST Spedali Civili - S.C. Ematologia
Brescia, Italy
Actively Recruiting
12
Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia
Florence, Italy
Actively Recruiting
13
Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia
Reggio Emilia, Italy
Actively Recruiting
14
A.O.U. Senese - U.O.C. Ematologia
Siena, Italy
Actively Recruiting
Research Team
U
Uffici Studi FIL
CONTACT
U
Uffici Studi FIL
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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