Prospective Birth Cohort Study on Allergies and Neurodevelopmental Disorders in Infants and Young Children in China

What this Trial Is About

Researchers are studying a birth cohort of infants to understand how allergies might be linked to neurodevelopmental disorders such as autism spectrum disorder ASD, attention deficit hyperactivity disorder ADHD, and learning disabilities. The study aims to identify factors in early life that influence these neurodevelopmental outcomes using standard diagnostic criteria DSM-5. This observational study is led by Qilu Hospital of Shandong University and focuses on children living in Jinan City and nearby areas in China. Infants in the study are divided into two groups based on allergy status an allergic group and a control group without allergies. They will be followed for up to six years, with periodic collection of biological samples like blood, urine, and feces. Growth measurements such as height and weight, along with developmental assessments like the GESELL test, will be recorded during regular follow-ups. Participants will undergo evaluations to monitor for signs of ASD, ADHD, or learning disabilities over the study period. Researchers will gather data through questionnaires and clinical examinations at multiple time points from 2023 to 2029. This long-term follow-up helps assess how early-life allergies may affect neurodevelopment. The study provides ongoing monitoring but does not involve any treatment interventions.

A Prospective Birth Cohort of Infants With Allergy and Neurodevelopmental Disorders in China