Actively Recruiting

Age: 18Years +
All Genders
ID07587216

Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment

Led by Tongji Hospital · Updated on 2026-06-04

800

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting a prospective, observational study to build a clinical database for liver cancer diagnosis and treatment. The study focuses on collecting comprehensive diagnostic, treatment, and long-term outcome information from patients treated at the Department of Hepatobiliary and Pancreatic Surgery. This database will help evaluate prognosis and treatment effectiveness in real-world clinical practice, supporting better clinical decisions in the future. Participants are grouped based on their treatment approach, including those undergoing liver resection surgery and those receiving systemic therapy combined with locoregional interventions such as PD-1 inhibitors and targeted drugs. The study observes these treatments without assigning interventions, reflecting real-world patient care. Throughout the study, participants' overall survival is tracked from treatment until death from any cause, with assessments up to 100 months. Researchers also monitor adverse events within 30 days after treatments. Data collection includes full diagnostic and therapeutic details alongside long-term follow-up to understand treatment outcomes and safety. The study will run from January 2026 through December 2029.

CONDITIONS

Brief Title

Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 6518 years at the time of signing the informed consent form
  • Clinically or histologically confirmed diagnosis of liver cancer
  • Receiving treatment and follow-up in Tongji Hospital
Not Eligible

You will not qualify if you...

  • Refuse participating in this study

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 30 days following surgery

Participants in the liver resection group undergo surgery to remove liver tumors and receive immediate post-operative care.

Approximately 6 post-operative visits

Treatment

Duration - Duration as per treatment plan

Participants in the non-surgery group receive systemic therapy with PD-1 inhibitors combined with targeted drugs and locoregional interventions.

Visit schedule according to treatment regimen

Long-term Monitoring

Duration - Up to 100 months

Participants are monitored for overall survival and adverse events following treatment.

Regular follow-up visits during monitoring period

Trial Site Locations

Total: 1 location

1

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030

Actively Recruiting

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Research Team

Q

Qi Cheng, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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