Actively Recruiting
Prospective Cohort for Early Detection of Liver Cancer
Led by University of Oxford · Updated on 2022-09-15
3000
Participants Needed
1
Research Sites
801 weeks
Total Duration
On this page
Sponsors
U
University of Oxford
Lead Sponsor
C
Cancer Research UK
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to recruit 3000 people with liver cirrhosis into a Prospective cohort for early detection of Liver cancer - the Pearl cohort. The study team believe that using a combination of novel tests may improve the detection of early Hepatocellular Carcinoma (HCC).
CONDITIONS
Official Title
Prospective Cohort for Early Detection of Liver Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of all genders aged over 18 years
- Able and willing to give informed consent to participate
- Diagnosed with cirrhosis Child-Pugh Class A or B
- Cirrhosis caused by chronic Hepatitis B or C infection, alcoholic liver disease, non-alcoholic fatty liver disease, or haemochromatosis
- Cirrhosis diagnosis confirmed by histology or validated non-invasive markers, varices evidence, or radiological signs of cirrhosis
You will not qualify if you...
- Current or past diagnosis of hepatocellular carcinoma
- Liver transplant recipients or those actively listed for transplantation
- Cirrhosis classified as Child-Pugh Class C
- Serious co-morbid conditions likely to cause death within 12 months as judged by a clinician
- Considered unsuitable for HCC surveillance by a clinician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hepatology Clinical Trial Unit, John Radcliffe Hospital
Oxford, Oxfordshire, United Kingdom, OX3 9DU
Actively Recruiting
Research Team
S
Study Coordinator
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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