Actively Recruiting
Prospective Cohort of Patients With Hepatocellular Carcinoma in France
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-06-10
5000
Participants Needed
1
Research Sites
431 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire, Amiens
Lead Sponsor
B
Biobanque de Picardie
Collaborating Sponsor
AI-Summary
What this Trial Is About
Hepatocellular carcinoma (HCC) occurs in 90% of cirrhosis primary liver cancers. In France, 8,500 new cases of HCC occur each year, and about 8,000 deaths per year are related to this cancer. The 5-year survival rate is 10%, one of the lowest survival rates of all cancer types. HCC raises a number of major challenges: HCC is discovered at a curable stage in only 25% of cases, reflecting the marked delay in the diagnosis of early stages. The state of knowledge about HCC is well behind that of other cancers (no biomarker, complex carcinogenesis, influence of the aetiology, poorly valorised data, etc.). Rapid technological progress requires large-scale studies to evaluate new diagnostic and therapeutic modalities. The CHIEF project constitutes a common basis knowledge for research project using prospectively collected data in patients with HCC, regardless of the cause and stage of the cancer. This project is a Multicentre longitudinal observational study of patients with HCC with prospective data collection on inclusion and patient follow-up. Constitution of a biological resources collection. 5,000 patients will be included over 2 years with a follow-up of patients of 5 years.
CONDITIONS
Official Title
Prospective Cohort of Patients With Hepatocellular Carcinoma in France
Who Can Participate
Eligibility Criteria
You may qualify if you...
- New cases of hepatocellular carcinoma (HCC)
- Suspected cases of HCC regardless of cause, stage, or treatment
- Known HCC patients receiving drug treatment for recurrence or progression
You will not qualify if you...
- Serious health conditions threatening life in the short term, except liver disease
- Vulnerable populations including minors, persons under guardianship or temporary guardianship, or individuals deprived of liberty by legal decision
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU Amiens
Amiens, France, 80480
Actively Recruiting
Research Team
O
Olivier Ganry, Pr
CONTACT
G
Gérard DUCOURNAU, Ing
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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