Actively Recruiting

Age: 18Years +
All Genders
NCT05284318

Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI.

Led by First Affiliated Hospital of Fujian Medical University · Updated on 2022-03-17

500

Participants Needed

1

Research Sites

265 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multicenter prospective cohort study in which patients were evaluated by inclusion and exclusion criteria before phase II revision surgery. Eligible patients will be included in this study after signing the informed consent form. After the second stage revision, according to the patient's symptoms and examination results, the attending physician used a reasonable antibiotic treatment scheme (including intravenous and oral medication). All patients voluntarily participated in the study and signed informed consent. During the treatment period, all prospective patients underwent clinical evaluation at the time points of 1, 3, 6, 12, 18 and 24 months after the start of antibiotic treatment after phase II revision. The infection control rate of patients was evaluated by follow-up at least 2 years after operation, so as to analyze the effect of antibiotic treatment course after two-stage revision of periprosthetic joint infection.

CONDITIONS

Official Title

Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of periprosthetic joint infection according to MSIS criteria
  • Received spacer implantation and completed at least 6 weeks of antibiotic treatment with clinical infection control
  • Age 18 years or older
  • Voluntary participation with physical and mental ability to undergo treatment and testing, signed informed consent, and ethics committee approval
Not Eligible

You will not qualify if you...

  • Follow-up data not available
  • Judged by researchers to no longer meet study criteria due to compliance problems

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Actively Recruiting

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Research Team

F

Fang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI. | DecenTrialz