Prospective Cohort Study of IgG4-Related Disease Patients Aged 18 to 75 in China Monitoring Disease Course and Treatment Response

What this Trial Is About

Researchers are investigating IgG4-related disease IgG4-RD, a condition marked by infiltration of tissues with IgG4-positive plasma cells, tissue fibrosis, and raised IgG4 levels in the blood. This observational cohort study aims to understand the disease course and how patients respond to treatment. The study includes patients with various manifestations of IgG4-RD, such as sclerosing pancreatitis, cholangitis, inflammatory pseudotumors, and others. Participants in this study will receive standard care for IgG4-RD and will be followed for at least six months. The study will gather detailed information on clinical symptoms, laboratory test results, and imaging findings to better characterize the disease and treatment effects. There are no experimental treatments all patients continue with their usual care. During the study, participants will undergo regular assessments including clinical evaluations and laboratory tests focusing on IgG4 levels and disease activity. The primary outcome is the clinical response measured at six months. The study will monitor participants over time to observe changes in their condition and treatment outcomes, helping to improve understanding of IgG4-RD.

A Prospective Cohort Study of IgG4RD in China