Actively Recruiting
A Prospective Cohort Study of Myasthenia Gravis in China
Led by Peking Union Medical College Hospital · Updated on 2024-01-12
202
Participants Needed
1
Research Sites
162 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective cohort study is to investigate long-term therapeutic strategies for myasthenia gravis (MG) and identify potential biomarkers. The main questions it aims to answer are: 1. Whether low-dose oral steroids may lead to a reduction in the recurrence rate among patients with MG. 2. To identify potential biomarkers that can predict disease progression and prognosis. This study recruits well-controlled patients with MG. Based on patient preferences and considerations such as coexisting conditions (e.g., uncontrolled hypertension, diabetes, severe osteoporosis, obesity), the participants will be non-randomly divided into two groups: a maintenance steroid therapy group and a withdrawal group (withdraw all immunosuppresants). Subsequently, these groups of patients will undergo long-term follow-up assessments.
CONDITIONS
Official Title
A Prospective Cohort Study of Myasthenia Gravis in China
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Attended the outpatient department of neurology of PUMCH from 9/30/2022 to 9/30/2024.
- Diagnosed as myasthenia gravis.
- Follow-up time at PUMCH greater than 6 months.
- The patient understood and signed the informed consent form.
You will not qualify if you...
- Comorbidities with other conditions that cause skeletal muscle weakness making clinical symptoms difficult to assess.
- Records related to comorbidities and medications were not available at baseline and during follow-up.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Y
Yuzhou Guan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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