Actively Recruiting
Clinical Characteristics, Prognosis and Biomarkers of Myasthenia Gravis: a Prospective Cohort Study in China
Led by Peking Union Medical College Hospital · Updated on 2024-01-12
202
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating long-term treatment strategies and biomarkers for myasthenia gravis (MG) in this prospective cohort study. The study focuses on whether maintaining low-dose oral steroids can reduce the recurrence rate of MG and aims to identify biomarkers that may predict disease progression and prognosis. Participants are patients with well-controlled MG. Participants are divided into two groups based on their preferences and medical considerations such as other health conditions. One group continues low-dose oral steroid therapy while the other group withdraws from all immunosuppressants. These groups will be monitored over a long-term period with regular assessments. During the study, participants will undergo follow-up evaluations to monitor MG relapses within two years after recruitment. Researchers will assess the timing of relapses, changes in MG assessment scales, and any adverse events related to steroid use. This ongoing monitoring aims to better understand treatment outcomes and disease progression in MG patients.
CONDITIONS
Brief Title
A Prospective Cohort Study of Myasthenia Gravis in China
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Attended the outpatient department of neurology of PUMCH from 9/30/2022 to 9/30/2024
- Diagnosed with myasthenia gravis
- Follow-up time at PUMCH longer than 6 months
- Patient understood and signed the informed consent form
You will not qualify if you...
- Other conditions causing skeletal muscle weakness that make symptoms hard to assess
- Missing records for comorbidities or medications at baseline or during follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 2 years
Participants are observed for relapse and changes in their condition while maintaining low-dose oral steroids or after withdrawing immunosuppressants.
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Y
Yuzhou Guan
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here