Actively Recruiting
A Prospective Cohort Study of Patients Suffering From Hand Osteoarthritis Symptoms
Led by University Hospital, Montpellier · Updated on 2025-09-30
150
Participants Needed
1
Research Sites
485 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The late-stage forms of degenerative osteoarthritis (OA) are very debilitating and less affordable to therapy. The main objective is to identify early onset symptoms of hand OA patients through imaging techniques (such as ultrasound and MRI). Our primary endpoint is to specify patients with high risk of radiological profression (X-ray).
CONDITIONS
Official Title
A Prospective Cohort Study of Patients Suffering From Hand Osteoarthritis Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Early digital osteoarthritis combining clinical and radiological definitions
- At least one of these symptoms: pain, stiffness, swelling, or deformity of finger joints (IPP and/or IPD)
- Age under 60 at the time of first symptoms
- Clinical symptoms present for less than 3 years
- Radiographic evidence with at least one affected PPI and/or IPD joint
- Presence of at least two radiographic signs: pinching, marginal subchondral condensation, or marginal osteophyte
- Signed consent form
You will not qualify if you...
- Rheumatoid arthritis, psoriasis arthritis, or other inflammatory rheumatism
- Metabolic diseases like gout, hemochromatosis, Wilson's disease, or congenital diseases such as dysplasia or osteogenesis imperfecta
- Advanced radiographic osteoarthritis (Kellgren Lawrence score =4) in any of the 10 studied joints
- Unable to provide a blood sample
- MRI contraindications
- Currently in exclusion period from another study
- Not affiliated with social insurance
- Pregnant or lactating women
- Vulnerable individuals as defined by law
- Elderly or disabled persons unable to consent
- Persons deprived of freedom by court or administrative order
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Rheumatology, CHU Montpellier
Montpellier, France, 34295
Actively Recruiting
Research Team
Y
Yves-Marie PERS, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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