Actively Recruiting

Age: 19Years +
FEMALE
NCT05893966

Prospective Cohort for Tumor Bed Boost Radiotherapy in HER2 Positive Breast Cancer

Led by Samsung Medical Center · Updated on 2025-06-29

400

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to analyze treatment outcomes related to tumor bed boost of postoperative radiation therapy in patient with HER2+ breast cancer who underwent breast conserving surgery. The main questions it aims to answer are: * 7-year ipsilateral breast tumor recurrence * 7-year disease-free survival * 7-year locoregional recurrence * 7-year overall survival * Adverse events of radiation therapy Participants will be assessed by multi-dimensional methods after radiation therapy: * Assessment for the disease status (disease-free or recurrence) including physical and radiologic examination * Assessment for the adverse events according to CTCAE version 5.0

CONDITIONS

Official Title

Prospective Cohort for Tumor Bed Boost Radiotherapy in HER2 Positive Breast Cancer

Who Can Participate

Age: 19Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients aged 19 years or older
  • Pathological confirmation of HER2 positive invasive breast cancer
  • Eastern Cooperative Oncology Group performance status of 0 to 2
  • Informed consent provided by the participant
Not Eligible

You will not qualify if you...

  • Pathological confirmation of ductal carcinoma in situ of the breast
  • Previous history of radiation therapy to the ipsilateral breast

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Samsung Medical Center

Seoul, South Korea, 06351

Actively Recruiting

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Research Team

H

Haeyoung Kim, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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