Actively Recruiting
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
Led by University of Aarhus · Updated on 2025-12-18
160
Participants Needed
5
Research Sites
1043 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol for all three Danish centres offering PTRA
CONDITIONS
Official Title
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- True resistant hypertension defined as requiring at least 3 antihypertensive drugs including a diuretic at optimal doses, with uncontrolled blood pressure confirmed by 24-hour monitoring
- Hypertension with intolerance or side effects to antihypertensive treatment confirmed by 24-hour monitoring
- Progressive renal insufficiency with a reduction in eGFR greater than 5 ml/min/1.73 m2 per year in patients with bilateral renal artery stenosis or one kidney
- Recurrent heart failure or pulmonary edema with resistant hypertension not explained by other conditions, confirmed by 24-hour monitoring
- Patients younger than 40 years with hypertension confirmed by 24-hour ambulatory blood pressure monitoring
- Presence of at least one of the above criteria
- Imaging tests (duplex doppler ultrasonography or renography) consistent with significant renal artery stenosis
- CT angiography or renal arteriography showing at least 70% narrowing of the renal artery lumen in one projection
You will not qualify if you...
- Bilateral significant renal artery stenosis where only one side is treated with PTRA
- PTRA performed on a kidney that handles 10% or less of total kidney function and has a kidney size less than 7 cm in length without blockage of the renin-angiotensin system
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Aalborg University Hospital
Aalborg, Denmark, 9000
Actively Recruiting
2
Aarhus University Hospital
Aarhus N, Denmark, 8200
Actively Recruiting
3
Glostrup University Hospital/ Rigshospitalet
Glostrup Municipality, Denmark, 2600
Actively Recruiting
4
Holbaek Hospital
Holbæk, Denmark, 4300
Actively Recruiting
5
Odense University Hospital
Odense C, Denmark, 5000
Actively Recruiting
Research Team
M
Mark Reinhard, PhD
CONTACT
K
Kent L Christensen, MD, DMSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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