Actively Recruiting

Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT07057466

Prospective Evaluation of AI-ECG for SHD Detection

Led by Imperial College London · Updated on 2026-03-09

590

Participants Needed

5

Research Sites

90 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to improve the early detection of undiagnosed heart disease, which causes serious health issues, hospital admissions, and high healthcare costs. Researchers are exploring how artificial intelligence (AI) can analyse routine heart tests, called electrocardiograms (ECGs), to detect heart problems. These tests can be done using both traditional ECG machines and portable, wearable devices like smartwatches, making it easier for people to monitor their heart health at home. While AI has shown promise using past data, this study will involve the collection of ECG data and subsequent testing of its accuracy in real-world settings to ensure it works well for both doctors and patients. The goal is to see if AI can identify conditions like heart muscle weakness, valve issues, and high lung pressure from the ECG data of patients. The researchers will also compare AI's detections with other blood tests commonly used to diagnose heart disease. The AI models that will be used are being tested for research and validation purposes only. They will not be used for clinical decision-making or providing information to influence diagnosis, treatment, or patient care during the study. The AI outputs are not shared with clinicians and will have no impact on the care pathway. This research will demonstrate if AI-powered ECG analysis - whether from traditional or portable devices - can provide a low-cost, non-invasive way to detect heart disease early and improve health assessments.

CONDITIONS

Official Title

Prospective Evaluation of AI-ECG for SHD Detection

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18-90 years
  • No prior formal diagnosis of heart failure, pulmonary hypertension, or valvular heart disease
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Severe arrhythmia or unstable cardiovascular disease
  • Prior formal diagnosis of heart failure, pulmonary hypertension, or valvular heart disease
  • Presence of a cardiac implantable electronic device such as a permanent pacemaker or implantable cardioverter defibrillator
  • Current or recent participation in any research studies prior to recruitment

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 5 locations

1

Southmead Hospital

Bristol, United Kingdom

Actively Recruiting

2

Chelsea and Westminster Hospital

London, United Kingdom

Actively Recruiting

3

Hammersmith Hospital

London, United Kingdom

Actively Recruiting

4

St Mary's Hospital

London, United Kingdom

Actively Recruiting

5

West Middlesex University Hospital

London, United Kingdom

Actively Recruiting

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Research Team

A

Ahmed YM El-Medany, MBChB, MRCP, MSc, FHEA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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