Actively Recruiting
Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
Led by International Spine Study Group Foundation · Updated on 2026-02-17
500
Participants Needed
12
Research Sites
700 weeks
Total Duration
On this page
Sponsors
I
International Spine Study Group Foundation
Lead Sponsor
N
NuVasive
Collaborating Sponsor
AI-Summary
What this Trial Is About
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
CONDITIONS
Official Title
Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years of age at the time of treatment
- Diagnosis of adult congenital, degenerative, idiopathic, neuromuscular, inflammatory, or iatrogenic spinal deformity
- EOS full body or standing 36" AP and Lateral images of entire spine
- Surgery scheduled within 6 months (if later, repeat PROMs and radiographic images required)
- Meet at least one radiographic criteria: PI-LL ≥ 25 degrees, thoracolumbar/lumbar scoliosis ≥ 20 degrees, SVA > 10 cm, or PT > 30
- OR meet at least one procedural criteria: surgery includes > 3 levels percutaneous posterior spinal instrumentation or 3 level stand-alone interbody; posterior UIV and LIV placed percutaneously; single-position surgery with ≥ 3 levels fused; staged ≥ 3 levels fused with percutaneous pedicle screws; 3 column osteotomy with percutaneous fixation; or ACR with percutaneous UIV and LIV screws
You will not qualify if you...
- Deformity caused by acute trauma
- Active spine tumor or infection
- Unable or unwilling to complete questionnaires
- Pregnant women
- Prisoners
- Planned open posterior spinal fusion (open anterior fusion such as ALIF allowed)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
Barrow Neurological Institute
Phoenix, Arizona, United States, 85013
Actively Recruiting
2
Shiley Center for Orthopaedic Research and Education at Scripps Clinic
La Jolla, California, United States, 92037
Actively Recruiting
3
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
4
University of California - San Francisco Medical Center
San Francisco, California, United States, 94143
Actively Recruiting
5
University of Miami
Miami, Florida, United States, 33125
Actively Recruiting
6
Rush University, Department of Neurosurgery
Chicago, Illinois, United States, 60612
Actively Recruiting
7
Louisiana Spine Institute
Shreveport, Louisiana, United States, 71101
Actively Recruiting
8
University of Michigan, Department of Neurosurgery
Ann Arbor, Michigan, United States, 48109
Completed
9
Columbia University - New York-Presbyterian Och Spine Hospital
New York, New York, United States, 10034
Actively Recruiting
10
Duke University Health System
Durham, North Carolina, United States, 27710
Actively Recruiting
11
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
12
Semmes-Murphey
Memphis, Tennessee, United States, 38120
Actively Recruiting
Research Team
C
Christine Baldus, MS
CONTACT
R
Ray Pinteric
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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