Actively Recruiting
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
Led by St. Jude Children's Research Hospital · Updated on 2026-03-27
100
Participants Needed
3
Research Sites
162 weeks
Total Duration
On this page
Sponsors
S
St. Jude Children's Research Hospital
Lead Sponsor
R
Rally Foundation for Childhood Cancer Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is being done to learn more about the short-term and long-term side effects of CAR-T cell therapy. Specifically, researchers want to know how often patients get infections, have delays in recovering blood cell counts and/or have damage to the nervous system.
CONDITIONS
Official Title
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must have received an initial systemically-administered CAR T cell infusion within the last 1-3 months (+/- 14 days).
- Initial infusion must be the first CAR T cell product they have received or a CAR T cell product received after an interval allogeneic HSCT.
- Age 30 years or younger at the time of CAR T cell infusion.
You will not qualify if you...
- Active malignancy other than the disease under study.
- Planned consolidative hematopoietic stem cell transplant within 3 months after CAR T cell infusion.
- Received or planned additional disease-directed therapy after CAR T cell infusion.
- Inability or unwillingness of participant or legal guardian to provide written informed consent.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
2
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
Actively Recruiting
3
Children's Hospital of Wisconsin.
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
R
Rebecca Epperly, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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