Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
NCT02208388

Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial

Led by Young-Hak Kim, MD, PhD · Updated on 2023-04-05

1000

Participants Needed

7

Research Sites

707 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization

CONDITIONS

Official Title

Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 20 and more
  • Diagnosed angina or angina equivalent symptom or positive exercise treadmill test
  • Patients with intermediate- or high-risk probability of CAD defined by Diamond and Forester
  • 70 % stenosis or more in coronary CTA
  • Willing to provide informed, written consent
Not Eligible

You will not qualify if you...

  • Requirement for surgical procedure
  • Cardiogenic shock and/or need for mechanical/pharmacologic hemodynamic support
  • Recent STEMI (<5 days)
  • Non STEMI, if the cardiac troponin is not stable or starting to decline
  • Left ventricular ejection fraction <30%
  • Life expectancy <2 years
  • Impaired renal function with an effective glomerular filtration rate less than 30mL/min/1.73 �b2 or creatinine more than 2.0 mg/dL
  • Undergoing evaluation for organ transplantation
  • Participation or planned participation in another cardiovascular clinical trial
  • Pregnancy
  • Inability to take dual antiplatelet therapy for six months
  • Previous CABG
  • Left main disease requiring revascularization
  • Any target lesion with in-stent restenosis
  • NYHA class 3 or 4a
  • Severe and persistent angina with severe limitation in everyday living activities (Canadian Cardiovascular Society grading Class IV)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Asan Medical Center

Seoul, Songpa-Gu, South Korea

Actively Recruiting

2

Hallym University Sacred Heart Hospital

Anyang, South Korea

Completed

3

Gangwon National Univ. Hospital

Chuncheon, South Korea

Completed

4

Keimyung University Dongsan Medical Center

Daegu, South Korea

Completed

5

Pusan National University Hospital

Pusan, South Korea

Enrolling by Invitation

6

Pusan National University Yangsan Hospital

Pusan, South Korea

Completed

7

Severance Hospital

Seoul, South Korea

Withdrawn

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Research Team

Y

Young-Hak Kim, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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