Actively Recruiting
Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2026-02-17
215
Participants Needed
1
Research Sites
616 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Computed Tomography (CT) is a scan that makes detailed pictures of the body. It uses radiation to do that. In 2011, about 85.3 million CT scans were done in the United States. But there is growing concern about the health effects of radiation. There are new and different ways to make CT pictures that use less radiation. Researchers want to learn whether these new methods create images that are similar to images from a traditional CT. Objective: \- To learn if new CT imaging methods with less radiation make images that are similar to traditional ways. Eligibility: \- Adults 18 years of age and older who are scheduled for a CT of the chest, abdomen and pelvis with contrast. Design: * Researchers will review participants medical records to see if they can be in this study. * Participants may have blood drawn from an arm vein by a needle stick. The blood will be used to make sure they can be in this study and that it is safe for them to have contrast. * During the participants CT scan appointment, one extra scan will be done using low radiation methods. * During a CT scan, the participant lies on a table. A large x-ray machine takes pictures of the body.
CONDITIONS
Official Title
Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical indication for a chest, abdomen, and pelvis CT with contrast
- Age equal to or greater than 18 years
- Able to understand and willing to sign the Informed Consent Form
- Clinical indication for a CT with or without contrast that includes the chest
You will not qualify if you...
- Pregnancy
- Serum creatinine greater than 1.5 mg/dL
- Clinical CT scan with more than one contrast imaging phase (for example, three phase liver)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
M
Margaret C Lowery, R.N.
CONTACT
M
Marcus Y Chen, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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