Actively Recruiting

Age: 18Years - 60Years
FEMALE
NCT05756244

PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

Led by University of Calgary · Updated on 2025-11-28

825

Participants Needed

14

Research Sites

351 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The PREP and GO study is an international multicentre prospective cohort evaluating anticoagulation management strategies around labor and delivery and the postpartum period.

CONDITIONS

Official Title

PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

Who Can Participate

Age: 18Years - 60Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Requires anticoagulation during the antepartum period of pregnancy for a VTE indication, including at least one of:
    1. Objectively confirmed VTE diagnosed during the current pregnancy
    2. Objectively confirmed VTE diagnosed in a prior pregnancy
    3. Objectively confirmed VTE diagnosed when not pregnant
    4. Inherited or acquired thrombophilia requiring anticoagulation
  • Receiving any dose or type of low-molecular-weight heparin during the antepartum period
Not Eligible

You will not qualify if you...

  • Anticoagulation for a non-VTE indication, including prosthetic heart valves, atrial fibrillation, prevention of placenta-mediated pregnancy complications, or prevention of recurrent pregnancy loss (participants can be included with a diagnosis of antiphospholipid syndrome with or without thrombotic events)
  • Unable to provide or declined consent
  • Planned delivery at home or birthing centre

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 14 locations

1

Duke University Hospital

Durham, North Carolina, United States, 27710

Actively Recruiting

2

Foothills Medical Centre

Calgary, Alberta, Canada, T2N 2T9

Actively Recruiting

3

Royal Alexandra Hospital

Edmonton, Alberta, Canada, T5H 3V9

Actively Recruiting

4

BC Women's Hospital and Health Centre

Vancouver, British Columbia, Canada, V6H 3N1

Actively Recruiting

5

St. Boniface Hospital

Winnipeg, Manitoba, Canada, R2H 2A6

Actively Recruiting

6

McMaster University Medical Centre

Hamilton, Ontario, Canada, L8N 3Z5

Actively Recruiting

7

The Ottawa Hospital - General Campus

Ottawa, Ontario, Canada, K1H 8L6

Actively Recruiting

8

Montfort Hospital

Ottawa, Ontario, Canada, K1K 0T2

Actively Recruiting

9

Mount Sinai Hospital

Toronto, Ontario, Canada, M5G 1X5

Actively Recruiting

10

CHU Sainte-Justine

Montreal, Quebec, Canada, H3T 1C5

Actively Recruiting

11

The Sir Mortimer B. Davis Jewish General Hospital

Montreal, Quebec, Canada, H3T 1E2

Actively Recruiting

12

Aarhus University Hospital

Aarhus, Denmark, 8200

Actively Recruiting

13

Le Centre Hospitalier Universitaire of Saint-Etienne

Saint-Etienne, France

Actively Recruiting

14

Hopitaux universitaires de Geneve

Geneva, Switzerland, 1205

Actively Recruiting

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Research Team

J

Jill Baxter, BSc

CONTACT

L

Leslie Skeith, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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